Arduino DUE + RADDS + TMC2208 UART

Hi all...im new here and I bought a RADDS Shield for arduino DUE and a couple of tmc2208 from waterrot...my question is how can I use the tmc2208 drivers in uart mode...i will use on X Y Z axis and for 2 extruder I will use lv8729 or a4988 drivers..
I'm searching on Google few days now to try to find an answer but I didn't find anything